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Calculates QUICKI, an index of insulin sensitivity derived from fasting insulin and fasting glucose: QUICKI = 1 / (log10 fasting insulin [µU/mL] + log10 fasting glucose [mg/dL]). Lower values indicate greater insulin resistance; the index is primarily a research and screening tool.
QUICKI = 1 ÷ ( log10 fasting insulin [µU/mL] + log10 fasting glucose [mg/dL] )
Descriptive — published means: nonobese ≈ 0.38, obese ≈ 0.33, diabetic ≈ 0.30
QUICKI is the reciprocal of the sum of logarithmic fasting insulin and glucose. Because both inputs are log-transformed, the index is less sensitive to high insulin values than HOMA-IR, which can become unstable at high insulin concentrations.
Specialty
EndocrinologyCategory
EndocrinologyDifficulty
Basic
Estimated Time
30 seconds
Version
1.0
Last Updated
2026-08-16
Formula
Keywords
Normal Range
Descriptive — published means: nonobese ≈ 0.38, obese ≈ 0.33, diabetic ≈ 0.30
| Classification | Range |
|---|---|
Nonobese (published mean) Katz et al., J Clin Endocrinol Metab 2000 | ≈ 0.38 |
Obese (published mean) Katz et al., J Clin Endocrinol Metab 2000 | ≈ 0.33 |
Diabetic (published mean) Katz et al., J Clin Endocrinol Metab 2000 | ≈ 0.30 |
Calculates QUICKI, an insulin sensitivity index from fasting insulin and glucose: QUICKI = 1 / (log10 fasting insulin [µU/mL] + log10 fasting glucose [mg/dL]).
Lower QUICKI values indicate greater insulin resistance. Published means: nonobese ≈ 0.38, obese ≈ 0.33, diabetic ≈ 0.30. There is no universal diagnostic cut-point.
QUICKI correlates with euglycemic-hyperinsulinemic clamp measures of insulin sensitivity using only a single fasting blood sample, enabling practical insulin resistance assessment.
A 40-year-old woman with obesity has fasting insulin 10 µU/mL and fasting glucose 90 mg/dL.
Inputs:
QUICKI = 1 / (log10(10) + log10(90)) = 1 / (1 + 1.9542) ≈ 0.34 — descriptive; compare with published means.
QUICKI uses log-transformed values, making it more stable at high insulin concentrations, where HOMA-IR can become unstable. In practice the two agree closely in most patients.
Fasting insulin in µU/mL and glucose in mg/dL. If glucose is in mmol/L, multiply by 18.018 to convert to mg/dL.
Conventional resistance index
Sensitivity framing
When insulin is unavailable
Disclaimer: This calculator is intended for educational and clinical decision support purposes only. QUICKI is a research-oriented surrogate and must not be used alone to diagnose insulin resistance or diabetes.