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Classifies acute kidney injury (AKI) severity using the KDIGO 2012 criteria based on serum creatinine changes and urine output. The highest applicable stage is assigned when multiple criteria are met.
Stage 1: Cr rise ≥0.3 mg/dL within 48h OR 1.5–1.9× baseline within 7 days; UO <0.5 mL/kg/h for 6–12h. Stage 2: Cr 2.0–2.9× baseline; UO <0.5 mL/kg/h for ≥12h. Stage 3: Cr ≥3.0× baseline OR Cr ≥4.0 mg/dL OR initiation of RRT; UO <0.3 mL/kg/h for ≥24h OR anuria for ≥12h.
No AKI
The KDIGO (Kidney Disease: Improving Global Outcomes) 2012 guidelines define AKI using serum creatinine and urine output criteria. AKI is staged 1–3 based on severity. The highest applicable stage from either criterion is assigned. KDIGO staging has replaced earlier RIFLE and AKIN criteria and is the current international standard for AKI classification.
Specialty
NephrologyCategory
NephrologyDifficulty
Basic
Estimated Time
30 seconds
Version
1.0
Last Updated
2026-08
Formula
Keywords
Normal Range
No AKI
| Classification | Range |
|---|---|
No AKI | None |
Stage 1 | Cr ≥0.3 mg/dL rise or 1.5–1.9× baseline; UO <0.5 mL/kg/h 6–12h |
Stage 2 | Cr 2.0–2.9× baseline; UO <0.5 mL/kg/h ≥12h |
Stage 3 | Cr ≥3.0× baseline or ≥4.0 mg/dL or RRT; UO <0.3 mL/kg/h ≥24h or anuria ≥12h |
Classifies acute kidney injury (AKI) severity using the KDIGO 2012 criteria based on serum creatinine changes and urine output.
Stage 0: No AKI. Stage 1: Cr rise ≥0.3 mg/dL or 1.5–1.9× baseline; UO <0.5 mL/kg/h for 6–12h. Stage 2: Cr 2.0–2.9× baseline; UO <0.5 mL/kg/h for ≥12h. Stage 3: Cr ≥3.0× baseline or ≥4.0 mg/dL or RRT; UO <0.3 mL/kg/h for ≥24h.
The KDIGO 2012 guidelines define AKI using serum creatinine and urine output criteria. AKI is staged 1–3 based on severity. The highest applicable stage from either criterion is assigned. KDIGO staging is the current international standard for AKI classification.
A patient's baseline creatinine was 1.0 mg/dL; current creatinine is 2.5 mg/dL.
Inputs:
Ratio = 2.5/1.0 = 2.5× baseline → KDIGO Stage 2 AKI. Consider urgent nephrology consultation and renal ultrasound.
KDIGO AKI staging is an international classification system for acute kidney injury severity. It uses serum creatinine changes and urine output measurements to assign stages 1–3, with Stage 3 being the most severe.
The highest applicable stage is assigned. For example, if creatinine criteria meet Stage 1 but urine output criteria meet Stage 2, the final stage is Stage 2.
If no baseline creatinine is available, use the lowest creatinine value from the preceding 7 days, or estimate baseline using the MDRD or CKD-EPI equation assuming normal kidney function. Clinical judgment is essential.
No. KDIGO staging classifies severity but does not distinguish between prerenal, intrarenal (structural), or postrenal causes. The underlying etiology must be determined separately.
KDIGO is the most current standard (2012) and incorporates elements of both RIFLE (2004) and AKIN (2007). KDIGO uses both creatinine and urine output criteria, defines AKI based on changes within 48 hours or 7 days, and is the recommended classification in current clinical practice.
Disclaimer: This calculator is intended for educational and clinical decision support. KDIGO staging should be used in conjunction with clinical assessment and is not a standalone diagnostic tool.
Current international standard for AKI staging and severity classification.
Does not distinguish prerenal vs. intrarenal vs. postrenal causes.
Estimating chronic GFR for CKD staging and monitoring.
For chronic kidney disease, not acute kidney injury staging.
Differentiating prerenal azotemia from ATN in AKI.
Does not stage AKI; assesses etiology of established AKI.